It's amazing that a small part of the brain ,no bigger than a pea, can have far reaching effects upon the physical body.
The pineal gland is deep within the center of the brain. It produces melatonin which assists in sleep. It also regulates what is known as the circadian rhythm, your internal body clock.
The circadian rhythm has an effect upon the Chinese Clock which affects your meridians.
Flouride, found in most US water supplies and in many toothpastes, settles around the pineal gland causing calcification which disturbs sleep patterns negatively affecting the brain.